That tune appears polyphonic (more than one note at a time) so good luck with that! Although, there were some games for the Spectrum which managed polyphony over the Spectrum's single digital audio output - 'Fairlight' springs to mind.
I have toyed with the idea of adapting 'Music Box' to play its output over MIDI, since I have several MIDI equipped synths here. The original tune in the manual is 'God Save The Queen'. I think that would sound quite good on distorted electric guitar, Hendrix style.
Who will write the first MK14 'tracker'?